Post-marketing surveillance of a non-steroidal anti-inflammatory analgesic Relifen tablet(nabumetone).

Assessing the Effects of Non-steroidal Anti-inflammatory Drugs on Antihypertensive Drug Therapy Using Post-Marketing Surveillance Database

BACKGROUND Antihypertensive and non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat many common diseases. However, it has been suspected that interactions between these drugs exist. Here, we assessed the interactions between non-selective NSAIDs and several classes of antihypertensive drugs. METHODS The study design was a cohort study using "The Antihypertensive Drug Database," w...

Non-steroidal anti-inflammatory drugs.

P 59: Non-Steroidal Anti-Inflammatory Drugs as a Prevention of Alzheimer Disease: Risks and Benefits

Alzheimer's disease (AD) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. The exact cause of Alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. This brings in mind using non-steroidal anti-inflammatory drugs (NSAID) as treatment or prevention of the disease. ...

Variation in postoperative non-steroidal anti-inflammatory analgesic use after colorectal surgery: a database analysis

BACKGROUND Non-steroid anti-inflammatory drugs (NSAIDs) have been proposed as part of a multimodal postoperative analgesia in patients operated for colorectal cancer. However, whether these drugs are prescribed and taken by the patients have not been evaluated. The aim of this study was to quantify the postoperative use of NSAIDs in these patients. METHODS Data from patients operated for colo...

Safety of non-steroidal anti-inflammatory drugs.

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in medical practice for treating pain, inflammation and degenerative joint diseases (for instance, arthritis). The use of traditional NSAIDs (tNSAIDs), however, is associated with an increased risk of minor and serious gastrointestinal (GI) events. It is estimated that in the European Union thousands of gastrointestinal complication...